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The upcoming discussion will update you about the differences between Apo-Enzyme and Co-Enzyme.

Difference # Apo-Enzyme:

1. It is protein part of the holoenzyme or con­jugate enzyme.

2. It is large in size.

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3. An apoenzyme is specific for an enzyme.

4. It takes part in only catalytic activity of the enzyme.

5. Apoenzyme does not help in group transfer.

6. Apoenzyme is thermolabile.

Difference # Co-Enzyme:

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1. Coenzyme is the non-protein organic group which gets attached to the apoenzyme to form holoenzyme or conjugate enzyme.

2. It is small in size.

3. A coenzyme can function as a cofactor for a number of enzymes carrying out that particular type of reaction.

4. It helps in removing a product of chemical reaction besides bringing contact between the substrate and the enzyme.

5. Coenzyme takes part in group transfer.

6. Coenzyme is heat stable.