The upcoming discussion will update you about the difference between DNA and RNA .
Difference # DNA:
1. They are formed by 4 types of monomeric units such as adenylate, guanylate, cytidylate and thymidylate.
2. The sugar moiety is deoxyribose.
3. They are present in nucleus, probably in the chromosomes.
4. They carry “genetic Information” from one generation of cells to the next and undergo mutation.
5. They contain 1,600 to 9,000 nucleotides. The molecules are long and thread-like having a length of about 250 times greater than their breadth. Their structure is highly complex.
6. They are concerned with protein synthesis.
7. They have 2 strands of antiparallel double helical structure.
8. Heat, acid and alkali denature DNA molecules.
9. They have ‘sense’ and ‘antisense’ strands.
Difference # RNA:
1. They are also formed by 4 types of monomeric units such as adenylate, guanylate, cytidylate, uracidylate.
2. The sugar moiety is D-ribose.
3. They are present in cytoplasm and nucleolus.
4. They carry no “genetic information” and undergo no mutation.
5. They contain 60 to 6,000 nucleotides. The molecules are un-branched. Their structure is less rigid.
6. They are also concerned with protein synthesis.
7. They exit as a single-stranded molecule.
8. The alkali hydrolysis is useful diagnostically and analytically.
9. The sequence of RNA molecule is the same as that of the ‘antisense’ strand of DNA.