In this article we will discuss about the oxidative decarboxylation of pyruvic acid. We know that anaerobiosis the pyruvic acid formed during glycolysis reacts with NADH which accumulates to give lactic acid (or ethanol) and thus permits the regeneration of NAD+. But when oxygen is available, NADH is reoxidized thanks to the electrons carrier system, and the pyruvic acid is [...]
The following points highlight the three possibilities of the transformation of pyruvic acid. The possibilities are: 1. Production of Lactic Acid 2. Alcoholic Fermentation 3. Formation of α-Glycerophosphate and Glycerol. Possibility # 1. Production of Lactic Acid: In animals, in muscle cells (where anaerobiosis conditions often prevail when oxygen utilization is more rapid than its input in cells) or in [...]
In this article we will discuss about the functions of the Krebs cycle, explained with the help of diagrams. Krebs made an outstanding contribution to the discovery of the operating mechanisms of this cycle which is also called tricarboxylic cycle or citric cycle, owing to the participation of various tricarboxylic acids, including citric acid. Before studying this cycle — which [...]