In this article we will discuss about the Physicochemical Organization of Chromosome. The major chemical components of the chromosomes are DNA, proteins (histones and non-histones) and small amount of RNA. Besides these, calcium and some other minerals are also present. Histones are basic proteins that are charged positively at neutral pH. Non-histone proteins are acidic. Histones are small proteins containing [...]
The following points highlight the top five techniques of chromosome banding. The techniques are: 1. C-Bands 2. G.Bands 3. Q-Bands 4. N-Bands 5. Other Techniques of Chromosome Banding. Chromosome Banding: Technique # 1. C-Bands: The technique of C-banding originated after the work of Pardue and Gall who reported that constitutive heterochromatin can be stained specifically by Giemsa-solution. Each chromosome possesses [...]
In this article we will discuss about the heterochromatin and euchromatin in eukaryotic chromosomes. The terms "heterochromatin" and "euchromatin" were given by Heitz in 1928-29, although they had been discovered much earlier. Heterochromatic blocks observed during interphase were earlier termed as pro-chromosomes. The substance of which eukaryotic chromosomes are composed is known as chromatin; it contains DNA, protein and a [...]