After reading this article you will learn about the metabolism of organophosphate esters in animals. Most of the phosphate insecticides are decomposed and excreted rapidly by mammals. Water soluble excretion products are excreted mainly through urine while excretion with the feces is very less. In mammal body toxically active cholinesterase (ChE) inhibitors are formed by […]
Metabolism of Organophosphate Esters in Animals | Toxicology
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Harmful Effects of Food Preservatives | Pharmacology
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In general, harmful effects of antibiotics drug/hormone residues in milk, meat, egg, poultry or fish may be drug resistance, hyper sensitivity, reduced reproductive performance, gastric, respiratory, neurological disease, growth inhibition heart disease, cancer. The addition of antibiotics in meat, milk and eggs must not be permitted. However, if use of antibiotic is necessary (e.g. for […]
Factors Decreasing the Bioavailability of Drugs | Toxicology
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This article throws light upon the three main factors decreasing the bioavailability of drugs. The factors are: 1. Inactivation 2. First Pass Effect 3. Enterohepatic Recycling. Factor # 1. Inactivation: Inactivation by gastric acid enzymes, bacterial flora. Factor # 2. First Pass Effect: Drug absorbed distal to the oral cavity and proximal to the rectum […]
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