Various tests have been devised for detecting spontaneous mutations in a population. Some of them are: 1. Replica Plating 2. Mutation Rates in Maize Endosperm and Drosophila 3. Detection of Mutations in Micro-Organisms. Test # 1. Replica Plating: In 1946 Luria and Delbrueck noticed one of the first cases of spontaneous mutation in a bacterial population. When E. coli cells [...]
The following points highlight the three types of point mutation. The types are: 1. Non-Sense Mutations 2. Missense Mutation 3. Silent Mutation. Type # 1. Non-Sense Mutations: Non-sense mutation is one type of point mutation. There are 64 codons that code for amino acid out of which three codons (UAA, UAG, UGA) are known as termination codons that do not [...]
In this article we will discuss about the chemical and physical types of mutagens. 1. Chemical Mutagens: Singer and Kusmierek (1982) have published an excellent review on chemical mutagenesis. Some of the chemical mutagens and mutagenesis are given in Table 9.3, and described below: i. Base Analogues: A base analogue is a chemical compound similar to one of the four [...]