In this article we will discuss about the history and induction of mutations. History of Mutation: The sudden heritable changes in genes, other than those due to Mendelian segregation and recombination constitute mutations. The idea of mutation first originated from observations of a Dutch botanist Hugo de Vries (in the 1880's) on variations in plants of Oenothera lamarckiana (evening primrose) [...]
In this article we discuss about the expression of mutations. The expression of mutation can be observed only when there occurs a detectable and altered phenotype. If a mutation occurs from a most prevalent wild type to a mutant form, it is called forward mutation. In forward mutation, a second mutation may take place resulting in appearance of a wild [...]
The following points highlight the top six uses of mutations in microorganisms. The uses are: 1. Determination of Function 2. Demonstration of Metabolic Pathways in Microorganisms 3. For Understanding The Metabolic Regulation 4. For Matching a Biochemical Entity with a Biological Function 5. For Locating the Site of Action of External Agents 6. For the Production of Useful Products. Use [...]